A Simple Key For cees dekker Unveiled

A Simple Key For cees dekker Unveiled

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Making use of single-molecule optical and AFM imaging and drive-spectroscopy tactics, we seek out to unravel the mechanistic elements of the composition and dynamics of chromosomes. Our investigation interests include:

1996, 1st mesoscopic demand density waves gadgets; and 1st electrical measurements on a single metal nanocluster involving nanoelectrodes

Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins

Because 2000, Dekker has shifted the leading concentrate of his function towards biophysics the place he studies the Homes of one biomolecules and cells utilizing the instruments of nanotechnology. This change of discipline was driven by his fascination for that remarkable functioning of biological molecular constructions, together with via the lengthy-phrase viewpoint that lots of fascinating discoveries could be predicted With this subject.[five] Present-day strains of research in his biophysics group are within the areas of:[6]

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Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,

You are a Christian. If you could possibly make such a artificial cell, would you be a person phase nearer to God, or would the position of https://www.ceesdekker.net God have diminished relatively yet again?

Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in the cooperative vogue

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Resolving the action measurement in condensin-driven DNA loop extrusion identifies ATP binding since the step-generating process

‘The concept there is such a issue for a commencing, a big bang, is currently a fascinating signpost to consider that there was a creator. But much more typically, and on The idea of pure rationality, I also arrive at a Christian interpretation of fact. An atheistic worldview is often a naturalistic worldview: essentially, there are actually only atoms and natural forces that we can measure.

‘That issues the synthetic mobile, as A part of the Dutch BaSyC initiative. Craig Venter seemed major-down in Individuals times and identified about five hundred genes that happen to be minimally needed for the performing cell. We want to glance bottom-up: how do we go from the few molecules to a whole Organic procedure?

2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of long-selection conformational changes in Mre11/DNA fix complexes; and to start with force measurements with a DNA molecule inside a nanopore

‘I am driven by surprise and inquiries. On a cloth amount I obtain answers in physics, but I encounter my deepest joy with God. That faith also drives my science And the way I take care of persons.